Hollywood star Reese Witherspoon marked her 49th birthday on March 22, 2025, surrounded by an outpouring of love from her A-list friends, including Jennifer Aniston and Jennifer Garner. The Legally Blonde actress, known for her radiant charm and powerhouse career, received adorable and heartfelt wishes that underscored the deep bonds she shares with her celebrity pals. As Witherspoon made another trip around the sun, Aniston and Garner took to social media to ensure her special day was even more memorable, delighting fans with glimpses into their enduring friendships.

Jennifer Aniston, who has shared the screen with Witherspoon in both the iconic sitcom Friends and the critically acclaimed series The Morning Show, led the birthday tributes with a touching Instagram Stories post on Saturday. Aniston shared a charming collage featuring snapshots of the duo from the sets of the two shows that have defined their onscreen chemistry. In Friends, Witherspoon famously played Jill Green, the spoiled younger sister of Aniston’s Rachel Green, while in The Morning Show, they portray co-anchors navigating the cutthroat world of broadcast journalism. Over the collage, Aniston wrote, “Happy birthday to my sister/co-anchor/source of Vitamin D I love you!!!!” The playful yet affectionate message highlighted their close-knit relationship, blending their professional collaboration with personal warmth.

Witherspoon was quick to reciprocate the love, reposting Aniston’s story with her own sweet note: “You’re the best sister and co-anchor there is @jenniferaniston.” The exchange melted hearts across social media, with fans reveling in the mutual admiration between the two stars. Their friendship, which spans over two decades, has grown from their early days on Friends to their current roles as executive producers and co-stars on The Morning Show, a series that has earned them both critical acclaim and award nominations. Aniston’s reference to Witherspoon as a “source of Vitamin D” nodded to the actress’s sunny disposition, a trait that has endeared her to colleagues and audiences alike.

Not to be outdone, Jennifer Garner also joined the birthday festivities with a warm tribute of her own. Garner, a longtime friend of Witherspoon’s, took to her social media to share a throwback photo from the premiere of the 2023 limited series The Last Thing He Told Me, which Witherspoon produced and Garner starred in. Alongside the image of the two smiling on the red carpet, Garner wrote, “Happy birthday to my favorite, most supportive boss lady friend.” The message celebrated Witherspoon not only as a cherished companion but also as a formidable force in Hollywood, reflecting her role as the founder of Hello Sunshine, the production company behind the project. Garner’s words painted a picture of a friendship built on mutual respect and unwavering support, a sentiment that resonates with their years of camaraderie.

Witherspoon’s 49th birthday celebration comes hot on the heels of another heartfelt moment in her social calendar. Just a week prior, on March 15, she took to Instagram to honor Eva Longoria Bastón’s birthday with a sweet post. The Big Little Lies star shared a photo of herself and Longoria, captioning it with a message that radiated affection: “Happy birthday to my gorgeous, talented, and inspiring friend @evalongoria! Love you so much!” The post underscored Witherspoon’s knack for nurturing meaningful relationships within the industry, a trait that shone brightly as her own birthday rolled around.

The tributes from Aniston and Garner were just the tip of the iceberg, as Witherspoon’s milestone birthday sparked a wave of love from fans and fellow celebrities alike. Known for her versatility—spanning romantic comedies like Sweet Home Alabama to gritty dramas like Wild, for which she earned an Oscar nomination—Witherspoon has carved out a legacy as both an actress and a producer championing women’s stories. Her company, Hello Sunshine, has become a beacon for female-driven narratives, producing hits like The Morning Show, Big Little Lies, and The Last Thing He Told Me. This birthday served as a reminder of her influence, not just onscreen but in the lives of those around her.

As the birthday wishes poured in, Witherspoon’s big day became a celebration of her talent, resilience, and the genuine connections she’s fostered over the years. Aniston and Garner’s notes were more than just social media shoutouts—they were testaments to a woman who balances stardom with sincerity. At 49, Reese Witherspoon continues to shine as brightly as ever, proving that her glow—much like the “Vitamin D” Aniston praised—comes from within. Here’s to another year of her lighting up Hollywood, one friendship and one project at a time.